There is a miraculous component that garners much attention, hailed as the secret weapon of health, and it is none other than Panax Notoginseng saponin. Panax notoginseng saponins are active compounds extracted from the roots of Panax notoginseng, possessing rich medicinal value and a wide range of application areas.

What is Panax Notoginseng Saponins?

Notoginseng saponins are one of the main active components of Panax notoginseng, belonging to the class of saponin compounds. Panax notoginseng, a plant native to southern China, has been widely used in traditional Chinese medicine for thousands of years. Notoginseng triterpene is the main medicinal component of Panax notoginseng, possessing various pharmacological effects such as antioxidant, anti-inflammatory, and anti-thrombotic properties. This product is a light yellow amorphous powder with a bitter taste and slight sweetness. It is obtained by extracting and separating effective medicinal components from high-quality Panax notoginseng, including more than 20 active saponin substances, 17 trace elements, proteins, abundant vitamins, polysaccharides, etc. Its functions mainly involve promoting blood circulation, eliminating blood stasis, and improving blood flow in the heart and brain. It is used for sequelae of cerebrovascular diseases, central retinal vein occlusion, anterior chamber hemorrhage, etc. The main side effects include occasional allergic rash, gastrointestinal discomfort, or minor bleeding such as gum bleeding and blood in sputum. Women may experience increased menstrual flow. Occasionally, blood pressure may rise, especially in the elderly. Therefore, it is not recommended to take Notoginseng triterpenes during menstruation to avoid affecting menstrual cycle and flow.

Properties of the Main Components:

Panax Notoginseng Saponin R1: Not available

Panax Notoginseng Saponin Rb1: White powder (ethanol-butanol). Melting point: 197-198°C. Specific rotation: +12.42 (c=0.91, methanol).

Panax Notoginseng Saponin Rg1: Triterpenoid derivatives. Crystalline powder (n-butanol-methyl ethyl ketone or ethyl acetate). Melting point: 194-196.5°C; specific rotation: +32 (pyridine). Specific rotation [α]D+24.80. Soluble in methanol, pyridine, and hot acetone, slightly soluble in ethyl acetate, and chloroform. Its acetylation product is soluble in methanol, pyridine, and hot acetone, and slightly soluble in ethyl acetate and chloroform. Its acetylation product is needle-like crystals with a melting point of 245°C.

Panax Notoginseng Saponin Rd: Triterpenoid derivatives. White powder (ethanol-acetic acid ethyl ester). Melting point: 206-209°C; specific rotation: +19.38 (c=1.03, methanol); specific rotation [α]D +17.8. o-methylated Panax Notoginseng Saponin Rd, white powder (methanol). Melting point: 91-93°C; specific rotation: +14.43 (c=0.97, chloroform). Its acetylation product is a crystalline powder with a melting point of 127°C.

Panax Notoginseng Saponin Re: Triterpenoid Derivatives. Colorless needle-like crystals (50% ethanol or methanol-water). Melting point: 201-203°C; specific rotation: 0~-1.00 (c=1.00, methanol). L-B reaction (+), Molisch reaction (+). Its full acetylation product is a crystalline powder with a melting point of 136°C. o-methylated Panax Notoginseng Saponin Re is pale pink (methanol), melting point: 115°C, specific rotation: +0.58 (c=1.02, chloroform).

Common Application Areas:

Medicinal Preparations: Notoginseng triterpenes are often used in the production of various medicinal preparations, especially in the field of traditional Chinese medicine. They are used to treat cardiovascular diseases, alleviate inflammation, and improve immune function. For example, Panax notoginseng saponins can be used to manufacture Panax notoginseng injections, Panax notoginseng tablets, etc., for the treatment of cardiovascular diseases and rheumatism.

Healthcare Products: Panax notoginseng saponins are also widely used in the healthcare product industry. Various Notoginseng triterpenes oral liquids, capsules, tablets, and other healthcare products are favored by consumers in the market. These healthcare products are often used to regulate blood lipids, enhance immunity, and improve physical fitness.

Cosmetics: Due to the antioxidant, anti-inflammatory, and anti-aging effects of Panax notoginseng triterpenes, they have applications in the cosmetics industry. Many skincare and anti-aging products contain Panax notoginseng triterpenes ingredients, used for skincare and delaying skin aging.

Functional Foods: Panax notoginseng triterpenes are also used in the production of functional foods, such as Panax notoginseng saponin oral liquids, Panax notoginseng saponin beverages, etc. These foods are often promoted for their effects in regulating blood lipids, enhancing immunity, and improving physical fitness.

In summary, Panax notoginseng saponins, as a natural active component, have broad application prospects. In the fields of medicine, healthcare products, cosmetics, and functional foods, they hold significant market potential. With the increasing awareness of health and the demand for natural medicinal components, it is believed that Notoginseng saponins will demonstrate even broader prospects in future development.

Panax Notoginseng Saponin