Persimmon leaf extract is a botanical extract derived from the leaves of the persimmon tree (Diospyros kaki).
According to the understanding of quality herb, In April the journal “molecular vision” published a report on the research achievements about “the persimmon leaf extract can improve dry eye syndrome”. In this study, the ethanol persimmon leaf extract was used for the mouse with dry eye syndrome. The widely used ophthalmic preservative benzyl benzalkonium chloride (BAC) induced the mouse dry eye syndrome.
To induce dry eye syndrome in normal mice, The scientists dripped 0.2% benzene tie ammonium chloride solution to their eyes 2 times per day for 14 days. Then the dry-eye mouse was given the persimmon leaf extract orally for 14 days, and the control group only dropped eye drops without preservatives into the mouse’s eyes. After that, the researchers determined the surface of the tear secretion volume (Schirmer test), break-up time (BUT), and fluorescein index. By terminal deoxynucleotidyl transferase-mediated dUTPNick end labeling (TUNEL) staining of the corneal epithelium apoptotic cell death. Use Western Blot Western blot interleukin -1α (IL-1α), IL-1β, IL-6, tumor necrosis factor α (TNF-α), and monocyte chemoattractant protein -1 (MCP-1) were analyzed. By immunofluorescence on corneal epithelium squamous epithelium a cytokeratin-10. The proliferation of the cornea using Ki-67 immunohistochemical analysis.
The results showed that persimmon leaf extract has the effect of extending the break-up time, reducing the fluorescein index, and Increasing the amount of tears, Can also inhibit the inflammation reaction in mice and the death of corneal epithelial cells. In addition, the squamous epithelium can be suppressed and the proliferation activity of corneal epithelial cells can be enhanced. The researchers believe that The future persimmon leaf may be an effective drug in the treatment of dry eye and its inhibitory components.
Here are some key details about persimmon leaf extract:
Composition:
The extract contains a variety of beneficial compounds, including:
Flavonoids – Such as quercetin, kaempferol, and myricetin
Tannins
Organic acids like malic acid and citric acid
Vitamins and minerals like vitamin C, vitamin E, and potassium
Traditional Uses:
In traditional Asian medicine, persimmon leaves have been used to treat a variety of conditions, including:
Diabetes and blood sugar regulation
Hypertension and cardiovascular health
Inflammation and skin disorders
Skincare Benefits:
In cosmetic applications, persimmon leaf extract is valued for its antioxidant and anti-inflammatory properties.
It may help soothe redness, fight free radicals, and improve skin texture and radiance.
Some studies suggest it may have skin-lightening effects and help reduce hyperpigmentation.
Applications:
Persimmon leaf extract is commonly found in skincare products like serums, moisturizers, and facial masks.
It can also be used in hair care products because it can strengthen and condition hair.
