Rutin

SPEC.:NF11  DAB  EP TEST METHOD: UV PLANT SOURCE:Scphora japonica L.

Rutin
SYNONYMS: Rutocide
SPEC.:NF11  DAB  EP
TEST METHOD: UV
PLANT SOURCE:Scphora japonica L.
CAS NO:153-18-4
MOLECULAR FORMULA & MOLECULAR Mass:C27H30O16   610.52

STRUCTURAL FORMULA:

153-18-4

CHARACTERISTIC:

Yellow or yellow-green powder or very fine needle-like crystal, odorless, tasteless, in the air gradually becomes darker, heated to 185-192 c into a jelly-brown. Difficult to dissolve in cold water (0.0013%), soluble in hot water (0.55%), hot methanol (11.2%), cold methanol (1.0%), hot ethanol (3.5 percent), cold ethanol (0.36%) cold pyridine (8.5 %), soluble in alkaline, and acid precipitation. Insoluble in other organic solvents.
PHARMACOLOGY:Rutin, the glycoside form of quercetin, is a bioflavonoid having aromatic trimeric heterocyclic structure. It is a naturally occurring pigment. It, chemically 3-[[6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl) -5,7-dihydroxy-4h-1-benzopyran-4-one, is a yellow to greenish crystalline powder melting at 190 c. Rutin is classified as vitamin p which increases the strength of the walls of the blood capillaries and regulates their permeability. Others classified as vitamin p are catechin, citrin, eriodictin, hesperetin, hesperidin, nobiletin, quercetin,sinensetin, and tangeretin. It is not a dietary essential but is known to have an effect on capillary disorders. It may also have a contribution to the total antioxidant activity and detoxifiers. It is also known to have pharmacological action as an anti-inflammatory, antihistaminic and antiviral agent.

CHEMICAL ANALYSIS:       

ITEMSRESULTS
Assay (anhydrous substance)95%—101.5%
Loss on drying5.5-9.0%
Residue on Ignition≤0.5%
Impurity Quercetin≤5%
Chlorophyll≤0.004%
Red pigments≤0.004%
Heavy Metal≤20ppm
Mesh Size95% pass 80 mesh

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